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There was no improvement in one-year progression-free survival rate and one-year overall survival rate in pediatric patients with newly diagnosed intrinsic brainstem gliomas who received capecitabine relative to a similar population of pediatric patients who participated in other clinical trials.

How it worksAntimetabolites kill cancer cells by acting as false building blocks in a cancer cell's genescausing the cancer cell to die as it gets ready to divide.

The chemotherapy drug capecitabine is included in a group of drugs known as anti-metabolitesThis group is focused on stopping the formation of new cancer cells and disrupting the DNA repair processwhich is how cancer cells are able to grow and multiplyCapecitabine is used for the treatment of a number of cancersincluding the breastbowelstomachpancreasand esophagus.

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